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Found 60 studies with search of: Etravirine OR TMC125 OR Intelence[TREATMENT] AND HIV [CONDITION]
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Rank Status Study
1 Completed TMC125-C229: TMC125 in HIV-1 Infected Subjects, Who Were Randomized to a TMC125 Treatment Arm in a Sponsor Selected TMC125 Trial and Were Treated for at Least 48 Weeks
Condition: HIV Infection
Intervention: Drug: TMC-125
2 Completed TMC 125 Blood Levels Study
Condition: HIV Infections
Interventions: Drug: TMC125 once daily;   Drug: TMC125 twice daily
3 Completed TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Subjects.
Conditions: HIV;   AIDS;   Fungal Infection
Intervention: Drug: TMC125
4 Completed TMC125-C211: Trial of TMC125 in HIV-1 Infected Subjects Who Were in a Sponsor Selected TMC125 Trial
Condition: HIV Infection
Intervention: Drug: TMC125
5 Completed TMC125-C223: TMC125 in HIV-1 Infected Subjects
Condition: HIV Infection
Intervention: Drug: TMC125
6 Completed TMC125-C227: A Phase II Randomized, Active-Controlled, Open Label Trial to Investigate the Efficacy and Tolerability of TMC125 in HIV-1 Infected Subjects, Who Are PI-Naive and With Documented Genotypic Evidence of NNRTI Resistance From Previous NNRTI Use
Condition: HIV Infection
Intervention: Drug: TMC125
7 Completed TMC125-TiDP2-C188: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Effect of Multiple-dose TMC125 on Buprenorphine and Norbuprenorphine Administered in HIV-negative Patients on Stable Buprenorphine/Naloxone Maintenance Therapy.
Conditions: HIV;   Pharmacokinetics
Intervention: Drug: TMC125
8 Active, not recruiting An Open-label Trial With TMC125 in Patients Who Have Virologically Failed in a DUET Trial (TMC125-C206 or TMC125-C216).
Condition: HIV-1
Intervention: Drug: TMC125
9 Recruiting A Study to Assess the Pharmacokinetics (Blood Levels) of TMC114 (Darunavir) Taken With TMC114r (Ritonavir), and TMC125 (Etravirine) in HIV-1 Infected Pregnant Women
Conditions: HIV;   HIV Infections;   Pregnancy
Interventions: Drug: TMC114 (darunavir);   Drug: TMC114r (ritonavir);   Drug: TMC125 (etravirine)
10 Completed TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.
Condition: HIV
Interventions: Drug: TMC125;   Drug: Placebo
11 Completed TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.
Condition: HIV
Interventions: Drug: TMC125;   Drug: Placebo
12 Completed TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers.
Condition: HIV
Intervention: Drug: Etravirine; Lopinavir; Ritonavir
13 Completed TMC125-TiDP35-C213: Safety and Antiviral Activity of Etravirine (TMC125) in Treatment-Experienced, HIV Infected Children and Adolescents.
Condition: HIV-1
Intervention: Drug: TMC125
14 Approved for marketing The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs.
Condition: HIV-1
Intervention: Drug: TMC125
15 Completed TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients
Conditions: Anti-Retroviral Agents;   HIV-1
Intervention: Drug: TMC125
16 Completed
Has Results
A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).
Condition: HIV-1 Infection
Intervention: Drug: TMC125; darunavir; ritonavir
17 Completed
Has Results
Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.
Condition: HIV
Intervention: Drug: TMC125, Darunavir; Ritonavir
18 Completed
Has Results
A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected Patients
Conditions: HIV Infection;   HIV;   Acquired Immunodeficiency Syndrome
Interventions: Drug: etravirine (ETR, TMC125);   Drug: efavirenz (EFV)
19 Completed Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125
Condition: HIV
Interventions: Drug: Etravirine;   Drug: Efavirenz
20 Active, not recruiting TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients
Conditions: HIV Infections;   Acquired Immunodeficiency Syndrome
Interventions: Drug: 48 weeks ATV/rtv 300/100mg once daily + ETR 200mg twice daily;   Drug: TDF 300mg;   Drug: ATV/rtv 400/100mg;   Drug: ATV/rtv 300/100mg

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